Spitzenkorper; phase contrast micrograph of A.nidulans after one day grown at 25°C in minimal media containing 17% gelatin showing spitzenkorper and fungal cell morphology
Spitzenkorper; phase contrast micrograph of A.nidulans after one day grown at 25°C in minimal media containing 17% gelatin showing spitzenkorper and fungal cell morphology
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Kindly provided by Sven Konzack and Reinhard Fischer Max-Planck-Institute for Terrestrial Microbiology, Karl von Frisch Str, D 35043 Marburg, Germany.
Mr RM is 80 and an ex-coal miner.He developed pneumoconiosis from exposure to coal dust. He also developed rheumatoid arthritis and the combination of this disease and pneumoconiosis is called Caplan’s syndrome.
His chest Xray in early 2015 shows extensive bilateral pulmonary shadowing with solid looking nodules superimposed on abnormal lung fields, contraction of his left lung with an elevated diaphragm and a large left upper lobe aspergilloma, displaying a classic air crescent. His CT scan from mid 2014 demonstrates a large aspergilloma in a cavity on the left, with marked pleural thickening around it, which is partially ‘calcified’ towards its base. Inferiorly on other images,remarkable pleural thickening and fibrotic irregular and spiculated nodules are seen, most partially calcified.