Date: 26 November 2013
Secondary metabolites, structure diagram: Trivial name – Warfarin metabolite 1
Copyright: n/a
Notes:
Species: A. nigerSystematic name: 1,2,5-Hexanetrione, 1-(2-hydroxyphenyl)-3-phenyl-Molecular formulae: C18H16O4Molecular weight: 296Chemical abstracts number: 119465-33-7Selected references: Microbial models of mammalian metabolism: production of novel a-diketone metabolites of warfarin and phenprocoumon by Aspergillus niger. Rizzo, Jinee D.; Davis, P. J. Coll. Pharm., Univ. Texas, Austin, TX, USA. Xenobiotica (1988), 18(12), 1425-37.
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Domestic crossbred cat with disseminated aspergillosis. Diff Quik stained squash preparation of material obtained from thoracotomy of a 3 year old domestic crossbred cat with invasive Aspergillus fumigatus infection. The cat had marked enlargement of the hilar lymph nodes that resulted in a partial tracheal obstruction. This smear was made from portions of the hilar lymph node resected at thoracotomy. Magnification x 132.
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English Pointer with nasal aspergillosis. Diff Quik stained cytological smear of material obtained from the frontal sinus of a 7 year old English Pointer with nasal aspergillosis. This infection was caused by Aspergillus fumigatus. Fungal hyphae are beautifully demonstrated by the Diff Quik stain. Magnification x 200.
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Nasal aspergillosis in a Schnauzer. Histological section of fungal plaques removed surgically from the frontal sinus of a 5 year old Schnauzer with nasal aspergillosis. This infection was caused by Aspergillus fumigatus. H & E; x 200.
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Disseminated aspergillosis in a German Shepherd. Masses of fungal hyphae in the renal pelvis of both kidneys in a young German Shepherd dog with disseminated Aspergillus terreus infection.
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Nasal aspergillosis. KOH preparation of fungal plaques surgically removed from the frontal sinus of a Schnauzer with nasal aspergillosis due to Aspergillus fumigatus.
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English Pointer with nasal aspergillosis. English Pointer with nasal aspergillosis treated by topical enilconazole injected through surgically inserted indwelling plastic tubes.
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German Shepherd with disseminated aspergillosis. Unilateral pyelonephritis in a German Shepherd dog with disseminated Aspergillus terreus infection.
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Rottweiler treated with indwelling plastic tubes. Photograph of a Rottweiler crossbred dog treated with indwelling plastic tubes placed surgically into the nasal cavity and frontal sinuses.
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Rottweiler crossbred dog with nasal aspergillosis. A Rottweiler crossbred dog with nasal aspergillosis due to Aspergillus fumigatus infection. Note the loss of pigment below the nostril on the worst affected side – this finding is suggestive of a diagnosis of chronic nasal aspergillosis in the dog.
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Disseminated aspergillosis in a German Shepherd. Hyphae of Aspergillus terreus in the urine of a young German Shepherd dog with disseminated aspergillosis. White blood cells are present in addition to the fungal hyphae. Wet preparation of urine; magnification x 132.