Date: 26 November 2013
Secondary metabolites, structure diagram: Trivial name – Tubingensin B
Copyright: n/a
Notes:
Species: A. tubingensisSystematic name: 1H-7,14b-Ethanobenzo[3,4]cyclohepta[1,2-b]carbazol-1-ol, 2,3,4,4a,5,6,7,9-octahydro-4,4a-dimethyl-7-(1-methylethyl)-, (1a,4a,4aa,7a,14bb)-(-)- (9CI)Molecular formulae: C28H35NOChemical abstracts number: 126663-32-9Selected references: TePaske, Mark R.; Gloer, James B.; Wicklow, Donald T.; Dowd, Patrick F. The structure of tubingensin B: a cytotoxic carbazole alkaloid from the sclerotia of Aspergillus tubingensis. Tetrahedron Letters (1989), 30(44), 5965-8. CODEN: TELEAY ISSN:
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4 Total obstruction of the sinuses due to inflamed mucosa. (Patient 04)
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1 Axial computed tomography (CT) scans of the frontal sinus.
A: due to the long lasting pressure of mucus, the bone of the anterior wall of frontal sinus is thinned out and elevated anteriorly, forming a bulge. B: same situation as depicted in fig A: the posterior bony wall of frontal sinus is thinned out and extremely elevated posteriorly towards the frontal lobe of the brain. As depicted on the scan, a thin bony layer covering the dura could be recognized intraoperatively -
2 Same patient as 1 and 3, frontal CT
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D. 6 months later, tenacious yellow secretions in L basal bronchial division
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C. After suction the material was seen to extend distally – obstructing the right basal stem bronchus
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B. After suction the material was seen to extend distally – obstructing the right basal stem bronchus