Secondary metabolites, structure diagram: Trivial name – tryptoquivaline I

Date: 26 November 2013

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Secondary metabolites, structure diagram: Trivial name – tryptoquivaline I

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Species: A. fumigatusSystematic name: Spiro[furan-2(5H),9′-[9H]imidazo[1,2-a]indole]-3′,5(2’H)-dione, 1′,3,4,9’a-tetrahydro-1′-hydroxy-2′,2′-dimethyl-4-[2-(2-methyl-1-oxopropyl)-4-oxo-3(4H)-quinazolinyl]-, (2S,4R,9’aS)-Molecular formulae: C27H26N4O6Molecular weight: 502.519Chemical abstracts number: 66180-23-2Selected references: Yamazaki, Mikio; Fujimoto, Haruhiro; Okuyama, Emi (Res. Inst. Chemobiodyn., Chiba Univ., Chiba, Japan). Chem. Pharm. Bull., 26(1), 111-17 (English) 1978.Aspergillus ribotoxins react with IgE and IgG antibodies of patients with allergic bronchopulmonary aspergillosis. KURUP VP ; KUMAR A ; KENEALY WR ; GREENBERGER PA JOURNAL OF LABORATORY AND CLINICAL MEDICINE; 123 (5). 1994. 749-756. SECONDARY METABOLITES MYCOTOXINS PRODUCED BY FUNGI COLONIZING CEREAL GRAIN IN STORAGE STRUCTURE AND PROPERTIES GOLINSKI P CHELKOWSKI, J. (ED.). DEVELOPMENTS IN FOOD SCIENCE, VOL. 26. CEREAL GRAIN: MYCOTOXINS, FUNGI AND QUALITY IN DRYING AND STORAGE. XXII+607P. ELSEVIER SCIENCE PUBLISHERS B.V.: AMSTERDAM, NETHERLANDS; (DIST. IN THE USA AND CANADA BY ELSEVIER SCIENCE PUBLISHING CO., INC.: NEW YORK, NEW YORK, USA). ILLUS. MAPS. ISBN 0-444-88554-4.; 0 (0). 1991

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Showing 10 posts of 2574 posts found.

  • Title

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  • Vascular thrombosis

    Vascular thrombosis. Medium power view (H&E) of a blood vessel occluded by fungal hyphae and thrombosis. Some fungal hyphae can be seen traversing the vessel wall.

    Vascular thrombosis

  • Elastase production

    Four colonies of Aspergillus on an agar plate containing rose bengal (to limit colony spending) and elastin fibres (light pink dots). Underneath and surrounding the colonies, the elastin fibres have gone, indicating enzymatic degradation

    patt19

  • Hyphae traversing elastin fibres

    High power view of elastin fibres in an arterial wall being forced apart by Aspergillus hyphae. As Aspergillus is angiotropic and produces an elastase, it was uncertain how it traversed vessel walls. It appears to do so without any dissolution of elastin fibres.

    patt18

  • Hyphae in arterial wall

    Medium power view (GMS) of hyphae seen within an arterial wall which is characteristic of angioinvasive Aspergillus.

    patt17

  • Intracellular hyphae

    High power view (H&E) of a branching mould, consistent with Aspergillus inside a giant cell in a patient with chronic granulomatous disease.

    patt15

  • Intracellular hyphae

    High power view (GMS) of an Aspergillus hypha within a giant cell in a patient with chronic granulomatous disease infected with Aspergillus.

    patt14

  • Sputum microscopy

    High power view (Papanicolau) of hyphae identified in sputum.

    patt13

  • Cerebral aspergillosis

    Medium power view (GMS) of the contents of a cerebral abscess in which there are hyphae typical of Aspergillus. Aspergillus fumigatus was grown from adjacent tissue.

    patt10

  • Bronchial aspergillosis

    Low power view (H&E) showing a pulmonary vein and a small bronchus infiltrated by fungal hyphae with associated necrotising inflammation.

    patt1

  • Bilateral A. fumigatus endophthalmitis in association with pulmonary and cerebral aspergillosis, complicating severe autoimmune disease treated with intense immunosuppression. Right eye.

    Bilateral A. fumigatus endophthalmitis in association with pulmonary and cerebral aspergillosis, complicating severe autoimmune disease treated with intense immunosuppression. Right eye.

    endopthalmitisrightRW