Secondary metabolites, structure diagram: Trivial name - territrem C

Date: 26 November 2013

Secondary metabolites, structure diagram: Trivial name – territrem C

Notes:

Species: A. terreusSystematic name: 4H,11H-Naphtho(2,1-b)pyrano(3,4-e)pyran-1,11(5H)-dione, 4a,6,6a,12,12a,12b-hexahydro-4a,12a-dihydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-4,4,6a,12b-tetramethyl-, (4aR-(4a-alpha,6a-beta,12a-alpha,12b-beta))-Molecular formulae: C28H32O9Molecular weight: 512.548Chemical abstracts number: 89020-33-7Selected references: Ling KH, Yang CK, Peng FT. Territrems, tremorgenic mycotoxins of Aspergillus terreus. Appl Environ Microbiol. 1979 Mar;37(3):355-7. Ling KH, Liou HH, Yang CM, Yang CK. Related Articles, Links Isolation, chemical structure, acute toxicity, and some physicochemical properties of territrem C from Aspergillus terreus. Appl Environ Microbiol. 1984 Jan;47(1):98-100. Chen JW, Ling KH. Territrems: Naturally Occurring Specific Irreversible Inhibitors of Acetylcholinesterase. J Biomed Sci. 1996 Jan;3(1):54-58.Toxicity: mouse LD50 intraperitoneal 6280ug/kg (6.28mg/kg) Applied and Environmental Microbiology. Vol. 47, Pg. 98, 1984.