Date: 26 November 2013
Secondary metabolites, structure diagram: Trivial name – terrein
Copyright: n/a
Notes:
Species: A. fischeri, A. lentulus, A. monodii, A. monodii, A. novofumigatus, A. olivicola, A. terreus, Emericella variecolor, Emericella venezuelensisSystematic name: 2-Cyclopenten-1-one, 4,5-dihydroxy-3-propenyl- 2-Cyclopenten-1-one, 4,5-dihydroxy-3-(1-propenyl)-Molecular formulae: C8H10O3Molecular weight: 154.163Chemical abstracts number: 582-46-7Selected references: Kiriyama, Noriki; Nitta, Keiichi; Sakaguchi, Yoshiaki; Taguchi, Yasuhisa; Yamamoto, Yuzuru (Fac. Pharm. Sci., Kanazawa Univ., Kanazawa, Japan). Chem. Pharm. Bull., 25(10), 2593-601 (English) 1977.Frisvad JC, Samson RA. Syst Appl Microbiol. 2004 Nov;27(6):672-80. Emericella venezuelensis, a new species with stellate ascospores producing sterigmatocystin and aflatoxin B1.Park SH, Kim DS, Kim WG, Ryoo IJ, Lee DH, Huh CH, Youn SW, Yoo ID, Park KC. Terrein: a new melanogenesis inhibitor and its mechanism. Cell Mol Life Sci. 2004 Nov;61(22):2878-85.
Images library
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4 Total obstruction of the sinuses due to inflamed mucosa. (Patient 04)
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1 Axial computed tomography (CT) scans of the frontal sinus.
A: due to the long lasting pressure of mucus, the bone of the anterior wall of frontal sinus is thinned out and elevated anteriorly, forming a bulge. B: same situation as depicted in fig A: the posterior bony wall of frontal sinus is thinned out and extremely elevated posteriorly towards the frontal lobe of the brain. As depicted on the scan, a thin bony layer covering the dura could be recognized intraoperatively
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2 Same patient as 1 and 3, frontal CT
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D. 6 months later, tenacious yellow secretions in L basal bronchial division
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C. After suction the material was seen to extend distally – obstructing the right basal stem bronchus
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B. After suction the material was seen to extend distally – obstructing the right basal stem bronchus
