Date: 26 November 2013
Secondary metabolites, structure diagram: Trivial name – Sulochrin, monochlor derivative
Copyright: n/a
Notes:
Species: A. aureusSystematic name: Benzoic acid, 2-(3-chloro-2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxy-, methyl esterMolecular formulae: C17H15ClO7Molecular weight: 366Chemical abstracts number: 89367-81-7Selected references: Inamori, Yoshihiko; Kato, Yoshiaki; Kubo, Mayuri; Kamiki, Teruo; Takemoto, Tsunematsu; Nomoto, Kyosuke. Studies on metabolites produced by Aspergillus terreus var. aureus. I. Chemical structures and antimicrobial activities of metabolites isolated from culture broth. Chemical & Pharmaceutical Bulletin (1983), 31(12), 4543-8.
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Bronchoscopic manifestations of Aspergillus tracheobronchitis. (a) Type I. Inflammatory infiltration, mucosa hyperaemia and plaques of pseudomembrane formation in the lumen without obvious airway occlusion. (b) Type II. Deep ulceration of the bronchial wall. (c) Type III. Significant airway occlusion by thick mucous plugs full of Aspergillus without definite deeper tissue invasion. (d) Type IV. Extensive tissue necrosis and pseudomembrane formation in the lumen with airway structures and severe airway occlusion (Wu 2010).
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High resolution CT showing centrilobular nodular opacities and branching linear opacities (tree-in-bud appearance) (Al-Alawi 2007).
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Chest X-ray showing poorly defined bilateral nodular opacities (Al-Alawi 2007).
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Gross pathologic specimen from autopsy shows the bronchial lumen covered by multiple whitish endobronchial nodules (arrows) (Franquet 2002).
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Invasive tracheobronchitis showing numerous nodules seen during bronchoscopy (Ronan D’Driscoll).
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Pseudomembranous seen overlying the bronchial mucosa (Tasci 2006).
