Date: 26 November 2013
Secondary metabolites, structure diagram: Trivial name – Orlandin
Copyright: n/a
Notes:
Species: A. nigerSystematic name: [8,8′-Bi-2H-1-benzopyran]-2,2′-dione, 7,7′-dihydroxy-4,4′-dimethoxy-5,5′-dimethyl-Molecular formulae: C22H18O8Molecular weight: 410Chemical abstracts number: 69975-77-5Selected references: Orlandin: a nontoxic fungal metabolite with plant growth inhibiting properties. Cutler, Horace G.; Crumley, Farrist G.; Cox, Richard H.; Hernandez, Oscar; Cole, Richard J.; Dorner, Joe W. Georgia Coastal Plain Exp. Stn., Sci. Educ. Adm., Tifton, GA, USA. Journal of Agricultural and Food Chemistry (1979), 27(3), 592-5.
Images library
-
Title
Legend
-
Nodules and areas of atelectasis are seen at both bases. He later died.
-
Further details
It is clearly a relatively small cavitary lesion, and the patient was almost asymptomatic. This response was a ‘stable’ response. The patient was included in the report Denning DW, Lee JY, Hostetler JS, Pappas P, Kauffman CA, Dewsnup DH, Galgiani JN, Graybill JR, Sugar AM, Catanzaro A, Gallis H, Perfect JR, Dockery B, Dismukes WE, Stevens DA, NIAID Mycoses Study Group multicenter trial of oral itraconazole therapy of invasive aspergillosis. Am J Med 1994; 97: 135-144.
, 
-
Well demarcated pulmonary infarction is well seen in this close-up of the lung at autopsy in a patient with histologically confirmed invasive aspergillosis. Angio invasion is characteristic of invasive aspergillosis, is associated with a worse prognosis, but is not always seen.
-
This 83 year old man presented with weight loss to a lung cancer clinic in mid 2003.
, 
, 
, 
, 
, 
