Date: 26 November 2013
Secondary metabolites, structure diagram: Trivial name – Orlandin
Copyright: n/a
Notes:
Species: A. nigerSystematic name: [8,8′-Bi-2H-1-benzopyran]-2,2′-dione, 7,7′-dihydroxy-4,4′-dimethoxy-5,5′-dimethyl-Molecular formulae: C22H18O8Molecular weight: 410Chemical abstracts number: 69975-77-5Selected references: Orlandin: a nontoxic fungal metabolite with plant growth inhibiting properties. Cutler, Horace G.; Crumley, Farrist G.; Cox, Richard H.; Hernandez, Oscar; Cole, Richard J.; Dorner, Joe W. Georgia Coastal Plain Exp. Stn., Sci. Educ. Adm., Tifton, GA, USA. Journal of Agricultural and Food Chemistry (1979), 27(3), 592-5.
Images library
-
Title
Legend
-
Necrotic lung tissue in culture
Af=Colony of Aspergillus fumigatus
B=bacterial colonies
L=lung tissue
-
A photograph of part of the upper lung lobe of an immunosuppressed patient. The lung tissue shows extenive areas of necrosis due to invasive colonisation.
-
A photograph of a cavity in the upper lobe of the lung of a patient with ankylosing spondylitis. Such cavitation,which may be confused with prior tuberculosis, can follow fibrosis.
-
Plugs stained with Methenamine/silverActively growing mycelia of the fungus are a deep brown/black. Counterstaining shows the dense mucus of the plugs as predominantly orange.
-
Sputum from an asthmatic patient showing plugs(casts). The development of plugs coincided with an increased prevalence and severity of episodes of asthma
-
microscopic characters Conidiophore stipes(C)1300-2800um long:Vesicles(V)40-70um wide,clavate:Phialides(Ph) uniseriate:Conidia(Con)3.5-4.0um long,smooth walled.
-
microscopic characters Conidiophore stipes(C)225-350um arising from hyphae(Hy):Vesicles(Ves)15-25um wide:Phialides(Ph)uniseriate:Conidia(Con)2.4-3.0um spherical to ovoid,roughened.
