Secondary metabolites, structure diagram: Trivial name – malformins

Date: 26 November 2013

  • malforminsweb

Prev
Next

Secondary metabolites, structure diagram: Trivial name – malformins

Copyright: n/a

Notes:

Species: A. nigerSystematic name: Cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl), cyclic (1®2)-disulfideMalformin AMolecular formulae: C23H39N5O5S2Molecular weight: 529.718Chemical abstracts number: 3022-92-2Selected references: Kim KW, Sugawara F, Yoshida S, Murofushi N, Takahashi N, Curtis RW. Structure of malformin B, a phytotoxic metabolite produced by Aspergillus niger. Biosci Biotechnol Biochem. 1993 May;57(5):787-91.Toxicity: mouse LD50 intraperitoneal 3100ug/kg (3.1mg/kg) EFFECTS: GASTROINTESTINAL: OTHER CHANGES. LIVER: OTHER CHANGES. KIDNEY, URETER, AND BLADDER: OTHER CHANGES Agricultural and Biological Chemistry. Vol. 39, Pg. 1325, 1975.

Images library

Showing 10 posts of 2574 posts found.

  • Title

    Legend

  • Aspergillus persii

    Culture plates on different media. A Colonies on CZ at 24oC, B on CYA at 20oC C on SAB at 37oC, D on CYA at 24oC

    persiicolonies

  • Sinusitis radiology

    D Sinusitis radiology with fluid level

  • Bronchiectasis

    C Bronchiectasis white cell scan (right) – left shows a normal scan for comparison

  • Bronchiectasis

    B Bronchogram showing bronchiectasis

  • Saccular bronchiectasis

    A Bronchogram showing saccular bronchiectasis

  • Mucous containing Charcot-Leyden crystals

    Mucous containing Charcot-Leyden crystals, stained with H & EA 57 year old woman presented with breathlessness. She had a history of mild asthma for which she occasionally took salbutamol inhaler puffs. The patient underwent a pneumonectomy because of the severity of her disease process, and uncertainty about the diagnosis, prior to serology results being obtained.Serology showed an IgE of 2600, with a strongly positive Aspergillus RAST test and weakly positive Aspergillus precipitins. Material re

  • EchinocandinB-kern 3d

  • Echinocandin B 3d

  • D-0870

  • Cilofungin 3d