Secondary metabolites, structure diagram: Trivial name – malformins

Date: 26 November 2013

Secondary metabolites, structure diagram: Trivial name – malformins

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Notes:

Species: A. nigerSystematic name: Cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl), cyclic (1®2)-disulfideMalformin AMolecular formulae: C23H39N5O5S2Molecular weight: 529.718Chemical abstracts number: 3022-92-2Selected references: Kim KW, Sugawara F, Yoshida S, Murofushi N, Takahashi N, Curtis RW. Structure of malformin B, a phytotoxic metabolite produced by Aspergillus niger. Biosci Biotechnol Biochem. 1993 May;57(5):787-91.Toxicity: mouse LD50 intraperitoneal 3100ug/kg (3.1mg/kg) EFFECTS: GASTROINTESTINAL: OTHER CHANGES. LIVER: OTHER CHANGES. KIDNEY, URETER, AND BLADDER: OTHER CHANGES Agricultural and Biological Chemistry. Vol. 39, Pg. 1325, 1975.

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  Notable people (obituaries)Charles Thom, 1872 - 1956David Gruby, 1810 - 1898Dorothy Fennell, 1926 - 1977Edouard Drouhet, 1919 - 2000Friedrich Staib, 1925 - 2011Gabriel Segretain, 1913 - 2008Guido Pontecorvo, 1907-1999Harry Marshall Ward, 1854-1906Ira F. Salkin 1941-2016Jack Pepys, 1914 - 1996JAMES CLARK GENTLES, 1921 - 1997John Hughes Bennett, 1812-1875John Pateman, 1926 - 2011John R. S. Fincham, 1926–2005Ken Haynes 1960 - 2018Kenneth Raper, 1908-1987Libero Ajello, 1916 - 2004MARGARET B. CHURCH, 1889-1976Philip Montagu D'Arcy Hart, 1900 - 2006Pier Antonio Micheli, 1679-1737Piero Martino, 1946–2007Raimond Sabouraud, 1864 - 1938Rudolf Virchow, 1821-1902William Ernest Dismukes 1939-2017

  Specific speciesA. alliaceusA. calidoustusA. candidusA. chevalieriA. clavatusA. costaricaensisA. cretensisA. flavusA. flocculosusA. fumigatusA. ibericusA. lacticoffeatusA. lanosusA. lentulusA. neobridgeriA. nidulansA. nidulans, Emericella nidulansA. nigerA. niveusA. ochraceopetaliformisA. ochraceusA. penicilloides, A. penicillioidesA. persiiA. piperisA. pseudoelegansA. pseudofisheriA. restrictusA. roseoglobulosusA. sclerotionigerA. steyniiA. sydowiiA. terreusA. udagawaeA. ustusA. westerdijkiaeE. herbariorumEurotium amstelodami, A. amstelodami

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