Date: 26 November 2013
Secondary metabolites, structure diagram: Trivial name – Isodihydroauroglaucin 2
Copyright: n/a
Notes:
Species: A. chevalieri, A. ruberSystematic name: Benzaldehyde, 2-(3E,5E)-3,5-heptadienyl-3,6-dihydroxy-5-(3-methyl-2-butenyl)-Molecular formulae: C19H24O3Molecular weight: 300Chemical abstracts number: 74886-31-0Selected references: Isolation and structures of two new metabolites from Aspergillus ruber. Hamasaki, Takashi; Fukunaga, Mamoru; Kimura, Yasuo; Hatsuda, Yuichi. Dep. Agric. Chem., Tottori Univ., Tottori, Japan. Agricultural and Biological Chemistry (1980), 44(7), 1685-7.
Images library
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The chest x-ray shows a patient who had a left lung transplanted in May 2003 for cryptogenic fibrosing alveolitis, which was diagnosed post-transplant as sarcoidosis.
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Gross pathology demonstrating the great pleural thickness and two cavities (upper lobe and superior segment of lower lobe) with fragments of fungal mass.
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Histopathological appearance of a fungus ball. Note a conidial head resulting from fungal exposure to the air.
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Histopathological appearance of a fungus ball caused by Scedosporium apiospermum. The presence of anneloconidia differentiates it from Aspergillus.
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Chronic necrotising aspergillosis. Hyaline hyphal and calcium oxalate crystals obtained by needle aspirate biopsy from a diabetic patient with chronic necrotizing aspergillosis caused by Aspergillus niger (Papanicolaou, x 100).
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Aspergillus niger fungus ball and acute oxalosis. Higher magnification of adjacent replicate section.
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Oxalate crystals within renal tubuli (H&E, phase contrast, x 100). This patient developed acute oxalosis.
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Lung surface. Fungus ball, severe parenchymal fibrosis and pleural thickening.
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