Date: 26 November 2013
Secondary metabolites, structure diagram: Trivial name – ditryptophenoline
Copyright: n/a
Notes:
Species: A. flavusSystematic name: [10b,10’b-Bi-10bH-pyrazino[1′,2′:1,5]pyrrolo[2,3-b]indole]-1,1′,4,4′-tetrone, 2,2′,3,3′,5a,5’a,6,6′,11,11′,11a,11’a-dodecahydro-2,2′-dimethyl-3,3′-bis(phenylmethyl)-, (3S,3’S,5aS,5’aS,10bS,10’bS,11aS,11’aS)-Molecular formulae: C42H40N6O4Molecular weight: 692Chemical abstracts number: 64947-43-9Selected references: Springer, James P.; Buechi, George; Kobbe, Brunhilde; Demain, Arnold L.; Clardy, Jon (Dep. Chem., Massachusetts Inst. Technol., Cambridge, Mass., USA). Tetrahedron Lett., (28), 2403-6 (English) 1977.
Images library
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Title
Legend
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Saggital section of the vertebral column of a dog with discospondylitis as part of disseminated aspergillosis due to A. terreus
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Discospondylitis – Radiograph of thoracolumbar vertebrae of a 2 year old, female German shepherd dog with disseminated aspergillosis demonstrating discospondylitis of T13-L1.
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Wasting and paraplegia – A 2 year old, male German shepherd dog with disseminated aspergillosis due to A. terreus. The marked loss of condition of this dog occurred within two months of initial diagnosis.
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A 2 year old, female German shephered dog with disseminated aspergillosis due to A. terreus. There is muscle wasting and paraplegia due to discospondylitis involving T13-L1.
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Draining sinus tract on left forelimb of a 4 year old, female Dalmatian with disseminated aspergillosis. There was an underlying osteomyelitis of distal humerus from which A. terreus was cultured.
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Aspergillus sinusitis in a dog. Long nosed dogs are at relatively high risk of Aspergillus sinusitis as shown in this example.
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English Pointer with nasal aspergillosis. Gram stained cytological smear of material obtained from the frontal sinus of a 7 year old English Pointer with nasal aspergillosis. This infection was caused by Aspergillus fumigatus. Magnification x 200.
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Domestic crossbred cat with disseminated aspergillosis. KOH preparation of material obtained from thoracotomy of a 3 year old domestic crossbred cat with invasive Aspergillus fumigatus infection. The cat had marked enlargement of the hilar lymph nodes that resulted in a partial tracheal obstruction. This preparation was made from portions of the hilar lymph node resected at thoracotomy. Magnification x 132.
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Rottweiler treated with indwelling plastic tubes. Photograph of a Rottweiler crossbred dog treated with indwelling plastic tubes placed surgically into the nasal cavity and frontal sinuses.
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Nasal aspergillosis in an English Pointer. Photograph of an English Pointer with nasal aspergillosis
Nasal aspergillosis in an English Pointer. Photograph of an English Pointer with nasal aspergillosis
