Date: 26 November 2013
Secondary metabolites, structure diagram: Trivial name – Dehydroaustin
Copyright: n/a
Notes:
Species: A. niger, A. stellatus, A. ustus, Emericella dentataSystematic name: Spiro[1H,4H,8H-3a,7a-epoxy-6,11b-methano-3H-furo[3,4-e][3]benzoxocin-9(10H),3′(6’H)-[2H]pyran]-1,4,6′-trione, 7-(acetyloxy)-6,7,11,11a-tetrahydro-2′,2′,3,6,11a-pentamethyl-8,12-bis(methylene)-, (3R,3’R,3aR,6S,7R,7aR,11aR,11bS)-Molecular formulae: C27H30O9Molecular weight: 498Chemical abstracts number: 82893-35-4Selected references: Maebayashi, Yukio; Okuyama, Emi; Yamazaki, Mikio; Katsube, Yukiteru. Structure of ED-1 isolated from Emericella dentata. Chemical & Pharmaceutical Bulletin (1982), 30(5), 1911-12. Simpson, Thomas J.; Stenzel, Desmond J.; Bartlett, Alan J.; O’Brien, Eugene; Holker, John S. E. Studies on fungal metabolites. Part 3. Carbon-13 NMR spectral and structural studies on austin and new related meroterpenoids from Aspergillus ustus, Aspergillus variecolor, and Penicillium diversum. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1982), (11), 2687-92.
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Culture plates on different media. A Colonies on CZ at 24oC, B on CYA at 20oC C on SAB at 37oC, D on CYA at 24oC
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Mucous containing Charcot-Leyden crystals, stained with H & EA 57 year old woman presented with breathlessness. She had a history of mild asthma for which she occasionally took salbutamol inhaler puffs. The patient underwent a pneumonectomy because of the severity of her disease process, and uncertainty about the diagnosis, prior to serology results being obtained.Serology showed an IgE of 2600, with a strongly positive Aspergillus RAST test and weakly positive Aspergillus precipitins. Material re
