Date: 26 November 2013
Secondary metabolites, structure diagram: Trivial name – Austamide
Copyright: n/a
Notes:
Species: A. ustusSystematic name: Spiro[2H-indole-2,7′ (8’H)-[3H,5H]pyrrolo[1′, 2′:4,5]pyrazino[1,2-a]azepine]-3,5′,12′(1H,2’H)-trione, 5’a, 6′-dihydro-8′,8′-dimethyl-, (5’aS-trans)-Molecular formulae: C21H21N3O3Molecular weight: 363.41Chemical abstracts number: 34427-31-1
Images library
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BAL specimen showing hyaline, septate hyphae consistent with Aspergillus, stained with Blankophor
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Mucous plug examined by light microscopy with KOH, showing a network of hyaline branching hyphae typical of Aspergillus, from a patient with ABPA.
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Corneal scraping stained with lactophenol cotton blue showing beaded septate hyphae not typical of either Fusarium spp or Aspergillus spp, being more consistent with a dematiceous (ie brown coloured) fungus
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Corneal scrape with lactophenol cotton blue shows separate hyphae with Fusarium spp or Aspergillus spp.
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A filamentous fungus in the CSF of a patient with meningitis that grew Candida albicans in culture subsequently.
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Transmission electron micrograph of a C. neoformans cell seen in CSF in an AIDS patients with remarkably little capsule present. These cells may be mistaken for lymphocytes.
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India ink preparation of CSF showing multiple yeasts with large capsules, and narrow buds to smaller daughter cells, typical of C. neoformans
