Secondary metabolites, structure diagram: Trivial name – Asparvenone derivative

Date: 26 November 2013

Secondary metabolites, structure diagram: Trivial name – Asparvenone derivative

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Notes:

Species: A. parvulusSystematic name: 1,4-Naphthalenedione, 6-ethyl-5-hydroxy-7-methoxy-Molecular formulae: C13H12O4Molecular weight: 232Chemical abstracts number: 56496-01-6Selected references: Metabolites of Aspergilli. II. Asparvenone and O-methylasparvenone, naphthalenones from Aspergillus parvulus. Chao, P. D.; Schiff, P. L., Jr.; Slatkin, D. J.; Knapp, J. E.; Chao, M.; Rosenstein, R. D. Sch. Pharm., Univ. Pittsburgh, Pittsburgh, PA, USA. Lloydia (1975), 38(3), 213-17.


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  • Culture plates on different media. A Colonies on CZ at 24oC, B on CYA at 20oC C on SAB at 37oC, D on CYA at 24oC

    persiicolonies

  • D Sinusitis radiology with fluid level

  • C Bronchiectasis white cell scan (right) – left shows a normal scan for comparison

  • B Bronchogram showing bronchiectasis

  • A Bronchogram showing saccular bronchiectasis

  • Mucous containing Charcot-Leyden crystals, stained with H & EA 57 year old woman presented with breathlessness. She had a history of mild asthma for which she occasionally took salbutamol inhaler puffs. The patient underwent a pneumonectomy because of the severity of her disease process, and uncertainty about the diagnosis, prior to serology results being obtained.Serology showed an IgE of 2600, with a strongly positive Aspergillus RAST test and weakly positive Aspergillus precipitins. Material re