Secondary metabolites, structure diagram: Trivial name – aranotin bisdethiobismethylthioacetyl biosynthesis

Date: 26 November 2013

Secondary metabolites, structure diagram: Trivial name – aranotin bisdethiobismethylthioacetyl biosynthesis

Copyright: n/a

Notes:

Species: A. terreusSystematic name: 2,3-Dithia-5,7-diazabicyclo[2.2.2]octane-6,8-dione-2,3-35S2, 1,4-bis(phenyl-4-t-methyl)-Molecular formulae: C18H14N2O2S2T2Molecular weight: Chemical abstracts number: 87869-08-7


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  • Culture plates on different media. A Colonies on CZ at 24oC, B on CYA at 20oC C on SAB at 37oC, D on CYA at 24oC

    persiicolonies

  • D Sinusitis radiology with fluid level

  • C Bronchiectasis white cell scan (right) – left shows a normal scan for comparison

  • B Bronchogram showing bronchiectasis

  • A Bronchogram showing saccular bronchiectasis

  • Mucous containing Charcot-Leyden crystals, stained with H & EA 57 year old woman presented with breathlessness. She had a history of mild asthma for which she occasionally took salbutamol inhaler puffs. The patient underwent a pneumonectomy because of the severity of her disease process, and uncertainty about the diagnosis, prior to serology results being obtained.Serology showed an IgE of 2600, with a strongly positive Aspergillus RAST test and weakly positive Aspergillus precipitins. Material re