Date: 26 November 2013
Secondary metabolites, structure diagram: Trivial name – Anditomin
Copyright: n/a
Notes:
Species: A. stellatusSystematic name: 9,15-Methano-3H,11H,13H-furo[3′,4′:3a,4]indeno[1,7a-g][2]benzoxepin-3,11,16-trione, 5,5a,6,7,8,9,10,10a,14,15,15a,15b-dodecahydro-5,5,9,15b-tetramethyl-14-methylene-, (5aR,7aS,9R,10aS,13aS,15R,15aR,15bR)-Molecular formulae: C25H30O5Molecular weight: 410Chemical abstracts number: 79874-93-4Selected references: Simpson, Thomas J.; Walkinshaw, Malcolm D. (Dep. Chem., Univ. Edinburgh, Edinburgh EH9 3JJ, Scot.). J. Chem. Soc., Chem. Commun., (17), 914-15 (English) 1981.
Images library
-
Title
Legend
-
The chest x-ray shows a patient who had a left lung transplanted in May 2003 for cryptogenic fibrosing alveolitis, which was diagnosed post-transplant as sarcoidosis.
-
Gross pathology demonstrating the great pleural thickness and two cavities (upper lobe and superior segment of lower lobe) with fragments of fungal mass.
-
Histopathological appearance of a fungus ball. Note a conidial head resulting from fungal exposure to the air.
-
Histopathological appearance of a fungus ball caused by Scedosporium apiospermum. The presence of anneloconidia differentiates it from Aspergillus.
-
Chronic necrotising aspergillosis. Hyaline hyphal and calcium oxalate crystals obtained by needle aspirate biopsy from a diabetic patient with chronic necrotizing aspergillosis caused by Aspergillus niger (Papanicolaou, x 100).
-
Aspergillus niger fungus ball and acute oxalosis. Higher magnification of adjacent replicate section.
-
Oxalate crystals within renal tubuli (H&E, phase contrast, x 100). This patient developed acute oxalosis.
-
Lung surface. Fungus ball, severe parenchymal fibrosis and pleural thickening.