Secondary metabolites, structure diagram: Trivial name – aflatoxin M1

Date: 26 November 2013

Secondary metabolites, structure diagram: Trivial name – aflatoxin M1

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Notes:

Species: A. flavus, A. parasiticusSystematic name: Cyclopenta[c]furo[3′,2′:4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-, (6aR-cis)-Molecular formulae: C17H12O7Molecular weight: 328.28Chemical abstracts number: 6795-23-9Selected references: Nakazato, Mitsuo; Morozumi, Satoshi; Saito, Kazuo; Fujinuma, Kenji; Nishima, Taichiro; Kasai, Nobuhiko (Dep. Food Hyg. and Nutr., Tokyo Metrop. Res. Lab. Public Health, Tokyo 169, Japan). Eisei Kagaku, 37(2), 107-16 (English) 1991.Toxicity: Slightly less toxic than aflatoxin B1 with an oral LD50 for the one day-old duckling 0.46 mg/kg body-weight. Significantly less carcinogenic than aflatoxin B1.


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    Legend

  • A. versicolor by microscopy showing very long thin conidiophores.

    aspvers4

  • Pigmentation of Aspergillus versicolor colonies ranged from pale green to greenish-beige, pink-green, dark green and brown. Reverse is usually reddish. The growth rate is usually slow. Cultured on Sabouraud dextrose agar with chloramphenicol.

    aspvers3

  • A Colonies on MEA after one week; B, C conidial heads with tip of conidiophire, x920; D conidial head, x 2330; E conidial heads x920

    aspvers2

  • A Colonies on MEA + 20% sucrose after one week; B detail of colony showing columnar conidial heads x 44 ; C conidial heads x 920; D conidia x2330

    A

  • Scanning electron micrograph photo of conidia. Scale bar: 1 µm.

    piperis F

  • Conidia-forming head and culture plate

    A

  • Cultures are grown on malt extract agar for 5-7 days at 30°C.
    Light microscopy-1000x stained with lacto-phenol and cotton blue.

    niger

  • A Colonies on MEA +20% sucrose after one week; B ascomata x 40; C conidiophores x 920; D ascospores x2330; E ascoma x 230; F portion of ascoma with asci and ascospores, x 920.

    Aspergillus_chevalieri