Date: 26 November 2013
Secondary metabolites, structure diagram: Trivial name – Aflatoxin G2a
Copyright: n/a
Notes:
Species: A. flavusSystematic name: 1H,12H-Furo[3′,2′:4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, 3,4,7a,9,10,10a-hexahydro-9-hydroxy-5-methoxy-Molecular formulae: C17H14O8Molecular weight: 346Chemical abstracts number: 20421-10-7Selected references: Dutton, M. F.; Heathcote, John G. Roy Coll. Advanced Technol., Salford, UK. Biochemical Journal (1966), 101(2), 21P-22P. CODEN: BIJOAK ISSN: 0264-6021. Journal written in English. CAN 66:36251 AN 1967:36251 CAPLUS
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Mr RM is 80 and an ex-coal miner.He developed pneumoconiosis from exposure to coal dust. He also developed rheumatoid arthritis and the combination of this disease and pneumoconiosis is called Caplan’s syndrome.
His chest Xray in early 2015 shows extensive bilateral pulmonary shadowing with solid looking nodules superimposed on abnormal lung fields, contraction of his left lung with an elevated diaphragm and a large left upper lobe aspergilloma, displaying a classic air crescent. His CT scan from mid 2014 demonstrates a large aspergilloma in a cavity on the left, with marked pleural thickening around it, which is partially ‘calcified’ towards its base. Inferiorly on other images,remarkable pleural thickening and fibrotic irregular and spiculated nodules are seen, most partially calcified.
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