Date: 26 November 2013
Secondary metabolites, structural diagram: Trivial name – Phenprocoumon metabolite 2
Copyright: n/a
Notes:
Species: A. nigerSystematic name: 2,4-Cyclohexadien-1-one, 6-(1-hydroxy-2-oxo-3-phenylpentylidene)-, (E)-Molecular formulae: C17H16O3Molecular weight: 268Chemical abstracts number: 119465-31-5Selected references: Microbial models of mammalian metabolism: production of novel a-diketone metabolites of warfarin and phenprocoumon by Aspergillus niger. Rizzo, Jinee D.; Davis, P. J. Coll. Pharm., Univ. Texas, Austin, TX, USA. Xenobiotica (1988), 18(12), 1425-37.
Images library
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BAL specimen showing hyaline, septate hyphae consistent with Aspergillus, stained with Blankophor
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Mucous plug examined by light microscopy with KOH, showing a network of hyaline branching hyphae typical of Aspergillus, from a patient with ABPA.
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Corneal scraping stained with lactophenol cotton blue showing beaded septate hyphae not typical of either Fusarium spp or Aspergillus spp, being more consistent with a dematiceous (ie brown coloured) fungus
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Corneal scrape with lactophenol cotton blue shows separate hyphae with Fusarium spp or Aspergillus spp.
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A filamentous fungus in the CSF of a patient with meningitis that grew Candida albicans in culture subsequently.
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Transmission electron micrograph of a C. neoformans cell seen in CSF in an AIDS patients with remarkably little capsule present. These cells may be mistaken for lymphocytes.
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India ink preparation of CSF showing multiple yeasts with large capsules, and narrow buds to smaller daughter cells, typical of C. neoformans
