Secondary metabolites, 3D structure: Trivial name – viomellein

Date: 26 November 2013

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Secondary metabolites, 3D structure: Trivial name – viomellein

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Species: A. melleus, A. ochraceusSystematic name: (8,8′-BI-1H-NAPHTHO(2,3-c)PYRAN)-1,1′,6,9-TETRONE, 3,3′,4,4′-TETRAHYDRO-7,7′-DIM (8,8′-Bi-1H-naphtho(2,3-c)pyran)-1,1′,6,9-tetrone, 3,3′,4,4′-tetrahydro-7,7′-dimethoxy-3,3′-dimethyl-9′,10,10′-trihydroxy-, (R-(R*,R*))-Molecular formulae: C30H24O11Molecular weight: 560.505Chemical abstracts number: 55625-78-0Selected references: Stack ME, Mislivec PB. Production of xanthomegnin and viomellein by isolates of Aspergillus ochraceus, Penicillium cyclopium, and Penicillium viridicatum. Appl Environ Microbiol. 1978 Oct;36(4):552-4. Filtenborg O, Frisvad JC, Svendsen JA. Simple screening method for molds producing intracellular mycotoxins in pure cultures. Appl Environ Microbiol. 1983 Feb;45(2):581-5. Robbers JE, Hong S, Tuite J, Carlton WW. Production of xanthomegnin and viomellein by species of Aspergillus correlated with mycotoxicosis produced in mice. Appl Environ Microbiol. 1978 Dec;36(6):819-23.Toxicity: Causes hepatic and renal damage in animals and associated with porcine nephropathy together with ochratoxins

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