Secondary metabolites, 3D structure: Trivial name – sphingofungin C

Date: 26 November 2013

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Secondary metabolites, 3D structure: Trivial name – sphingofungin C

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Species: A. fumigatusSystematic name: 6-Eicosenoic acid, 5-(acetyloxy)-2-amino-3,4,14-trihydroxy-Molecular formulae: C22H41NO7Molecular weight: 431.563Chemical abstracts number: 121025-46-5Selected references: VanMiddlesworth F, Giacobbe RA, Lopez M, Garrity G, Bland JA, Bartizal K, Fromtling RA, Polishook J, Zweerink M, Edison AM, et al. J Antibiot (Tokyo). 1992 Jun;45(6):861-7. Sphingofungins A, B, C, and D; a new family of antifungal agents. I. Fermentation, isolation, and biological activity.Zweerink MM, Edison AM, Wells GB, Pinto W, Lester RL. Characterization of a novel, potent, and specific inhibitor of serine palmitoyltransferase. J Biol Chem. 1992 Dec 15;267(35):25032-8. FUMONISINS POWELL RG ; PLATTNER RD PELLETIER, S. W. (ED.). ALKALOIDS: CHEMICAL AND BIOLOGICAL PERSPECTIVES, VOL. 9. XV+286P. PERGAMON PRESS LTD: OXFORD, ENGLAND, UK; TARRYTOWN, NEW YORK, USA. ISBN 0-08-042089-3.; 0 (0). 1995. 247-278.

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    Reference: Muco-cutaneous retinoid effects and facial erythema related to the novel triazole antifungal agent voriconazole. Denning, DW & Griffiths, CEM. Clin.Exp Dermatol 2001, 26(8), 648-53.
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