Date: 26 November 2013
Secondary metabolites, 3D structure: Trivial name – Norisotryptoquivaline
Copyright: n/a
Notes:
Species A. fumigatusSystematic name Spiro[furan-2(5H),9′-[9H]imidazo[1,2-a]indole]-3′,5(2’H)-dione, 1′-(acetyloxy)-1′,3,4,9’a-tetrahydro-4-[2-[(1S)-1-hydroxy-2-methylpropyl]-4-oxo-3(4H)-quinazolinyl]-2′-methyl-, (2S,2’S,4R,9’aS)-Molecular formulae C28H28N4O7Molecular weight 532Chemical abstracts number 61897-84-5Selected references Yamazaki, Mikio; Okuyama, Emi; Maebayashi, Yukio (Res. Inst. Chemobiodyn., Chiba Univ., Chiba, Japan). Chem. Pharm. Bull., 27(7), 1611-17 (English) 1979.
Images library
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The periphery of the fungus ball is deeply eosinophilic because of the deposition of Splendore-Hoeppli material.
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Single fungal ball, moving. Radiographic appearance of a fungus ball, showing movement as the patient’s position changes.
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Oxalate crystals in the cavity wall surrounding an Aspergillus niger fungus ball (H&E, dark field, x 25).
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Aspergilloma patient. Gross pathology appearance of a fungus ball.
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Conidiophores of Aspergillus fumigatus in the mass of the fungal ball surrounded by mycelia (H&E, x 400).
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Aspergillus niger fungal ball. Calcium oxalate crystals in Aspergillus niger fungal ball. Also shown are darkly pigmented, rough-walled conidia associated with Aspergillus niger infection.
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Aspergillus niger fungus ball within an old tuberculous cavern. This patient had diabetes, a disease commonly associated with A. niger infection.