Date: 26 November 2013
Secondary metabolites, 3D structure: Trivial name – Nigragillin
Copyright: n/a
Notes:
Species: A. (species not defined)Systematic name: Piperazine, 1,2,5-trimethyl-4-[(2E,4E)-1-oxo-2,4-hexadienyl]-, (2R,5S)-rel-(+)-Molecular formulae: C13H22N2OMolecular weight: 222Chemical abstracts number: 24779-38-2Selected references: Isolation and identification of nigragillin as an insecticidal metabolite produced by Aspergillus niger. Isogai, Akira; Horii, Tetsuo; Suzuki, Akinori; Murakoshi, Shigeo; Ikeda, Katsutoshi; Sato, Shouhachi; Tamura, Saburo. Dep. Agric. Chem., Univ. Tokyo, Tokyo, Japan. Agricultural and Biological Chemistry (1975), 39(3), 739-40. CODEN: ABCHA6 ISSN: 0002-1369.
Images library
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The periphery of the fungus ball is deeply eosinophilic because of the deposition of Splendore-Hoeppli material.
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Single fungal ball, moving. Radiographic appearance of a fungus ball, showing movement as the patient’s position changes.
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Oxalate crystals in the cavity wall surrounding an Aspergillus niger fungus ball (H&E, dark field, x 25).
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Aspergilloma patient. Gross pathology appearance of a fungus ball.
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Conidiophores of Aspergillus fumigatus in the mass of the fungal ball surrounded by mycelia (H&E, x 400).
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Aspergillus niger fungal ball. Calcium oxalate crystals in Aspergillus niger fungal ball. Also shown are darkly pigmented, rough-walled conidia associated with Aspergillus niger infection.
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Aspergillus niger fungus ball within an old tuberculous cavern. This patient had diabetes, a disease commonly associated with A. niger infection.