Date: 26 November 2013
Secondary metabolites, 3D structure: Trivial name – Nigragillin
Copyright: n/a
Notes:
Species: A. (species not defined)Systematic name: Piperazine, 1,2,5-trimethyl-4-[(2E,4E)-1-oxo-2,4-hexadienyl]-, (2R,5S)-rel-(+)-Molecular formulae: C13H22N2OMolecular weight: 222Chemical abstracts number: 24779-38-2Selected references: Isolation and identification of nigragillin as an insecticidal metabolite produced by Aspergillus niger. Isogai, Akira; Horii, Tetsuo; Suzuki, Akinori; Murakoshi, Shigeo; Ikeda, Katsutoshi; Sato, Shouhachi; Tamura, Saburo. Dep. Agric. Chem., Univ. Tokyo, Tokyo, Japan. Agricultural and Biological Chemistry (1975), 39(3), 739-40. CODEN: ABCHA6 ISSN: 0002-1369.
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Bronchoscopic manifestations of Aspergillus tracheobronchitis. (a) Type I. Inflammatory infiltration, mucosa hyperaemia and plaques of pseudomembrane formation in the lumen without obvious airway occlusion. (b) Type II. Deep ulceration of the bronchial wall. (c) Type III. Significant airway occlusion by thick mucous plugs full of Aspergillus without definite deeper tissue invasion. (d) Type IV. Extensive tissue necrosis and pseudomembrane formation in the lumen with airway structures and severe airway occlusion (Wu 2010).
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High resolution CT showing centrilobular nodular opacities and branching linear opacities (tree-in-bud appearance) (Al-Alawi 2007).
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Chest X-ray showing poorly defined bilateral nodular opacities (Al-Alawi 2007).
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Gross pathologic specimen from autopsy shows the bronchial lumen covered by multiple whitish endobronchial nodules (arrows) (Franquet 2002).
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Invasive tracheobronchitis showing numerous nodules seen during bronchoscopy (Ronan D’Driscoll).
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Pseudomembranous seen overlying the bronchial mucosa (Tasci 2006).
