Secondary metabolites, 3D structure: Trivial name – neoechinuline

Date: 26 November 2013

Secondary metabolites, 3D structure: Trivial name – neoechinuline

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Notes:

Species: A. amstelodamiSystematic name: (6E)-6-([2-(1,1-Dimethyl-2-propenyl)-6-(3-methyl-2-butenyl)-1H-indol-3-yl]methylene)-2,3,5-piperazinetrione 2,3,5-Piperazinetrione, 6-[[2-(1,1-dimethylallyl)-6-(3-methyl-2-butenyl)indol-3-yl]methylene]- Piperazinetrione, [[2-(1,1-dimethyl-2-propenyl)-6-Molecular formulae: C23H25N3O3Molecular weight: 391.463Chemical abstracts number: 25644-25-1Selected references: Selva A, Traldi P. Biomed Mass Spectrom. 1977 Jun;4(3):143-5. The electron impact induced fragmentation of Aspergillus amstelodami alkaloids and derivatives.


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  • Culture plates on different media. A Colonies on CZ at 24oC, B on CYA at 20oC C on SAB at 37oC, D on CYA at 24oC

    persiicolonies

  • D Sinusitis radiology with fluid level

  • C Bronchiectasis white cell scan (right) – left shows a normal scan for comparison

  • B Bronchogram showing bronchiectasis

  • A Bronchogram showing saccular bronchiectasis

  • Mucous containing Charcot-Leyden crystals, stained with H & EA 57 year old woman presented with breathlessness. She had a history of mild asthma for which she occasionally took salbutamol inhaler puffs. The patient underwent a pneumonectomy because of the severity of her disease process, and uncertainty about the diagnosis, prior to serology results being obtained.Serology showed an IgE of 2600, with a strongly positive Aspergillus RAST test and weakly positive Aspergillus precipitins. Material re