Date: 26 November 2013
Secondary metabolites, 3D structure: Trivial name – Mulundocandin
Copyright: n/a
Notes:
Species: A. (species not defined)Systematic name: 1-[4,5-dihydroxy-N2-(12-methyl-1-oxotetradecyl)ornithine]-5-serine-; 1H-Dipyrrolo[2,1-c:2′,1′-l][1,4,7,10,13,16]hexaazacycloheneicosineMolecular formulae: C48 H77 N7 O16Molecular weight: Chemical abstracts number: 108351-20-8
Images library
-
Title
Legend
-
High resolution CT scan images with reconstruction of 1mm thick slices at approximately 10mm increments. The scan shows moderately severe multi-lobar cylindrical and varicose bronchiectasis predominantly centrally and in the upper lungs. There is no mucus plugging seen.
The features are in keeping with allergic bronchopulmonary aspergillosis
, 
, 
-
pt.SB – 6/10/98 – bronchocentric granulomatosis. CT scan showing multiple small nodules of variable size in both lung fields, apparently close to the vascular bundles.
-
Bronchial oedema.Remarkably oedematous bronchial mucosa, as seen in ABPA.
-
An example of longstanding allergic bronchopulmonary aspergillosis in a patient who has been steroid dependent for over 15 years showing remarkable kyphoscoliosis and honey combing and fibrosis of both lungs.
-
Recurrent pulmonary shadows 1. 6 Jan 1988 – chest radiograph showing right hilar enlargement, consistent with ABPA.
Recurrent pulmonary shadows 1. 3 Feb 1989 – chest radiograph showing right upper-lobe consolidation and contraction consistent with obstruction of RUL bronchus, in ABPA.
Clearing of pulmonary shadows 3, pt BJ. 5 April 1989 – resolution of shadows seen in February, with a course of corticosteroids.
Recurrence of pulmonary shadows 4, pt BJ. 2 September 1989 – recurrence of pulmonary shadows with an exacerbation of ABPA.
Central bronchiectasis, pt BJ. CT scan of thorax October 1989 showing central bronchiectasis, characteristic of ABPA (and cystic fibrosis).
, 
, 
, 
, 
-
A typical example of a wet mount of a sputum sample from a patient with allergic bronchopulmonary aspergillosis.
