Date: 26 November 2013
Secondary metabolites, 3D structure: Trivial name – maltoryzine
Copyright: n/a
Notes:
Species: A. oryzae var. microsporusSystematic name: 3-Penten-1-one, 1-(2,3,6-trihydroxyphenyl)- (9CI)Other Names: 3-Pentenophenone, 2′,3′,6′-trihydroxy- (7CI,8CI); Maltoryzin; MaltoryzineMolecular formulae: C11H12O4Molecular weight: 208.211Chemical abstracts number: 6826-42-2Selected references: IIZUKA H, IIDA M. Maltoryzine, a new toxic metabolite produced by a strain of Aspergillus oryzae var. microsporus isolated from the poisonous malt sprout. Nature. 1962 Nov 17;196:681-2.Toxicity: mouse LD50 intraperitoneal 3mg/kg (3mg/kg) EFFECTS: PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) Food and Cosmetics Toxicology. Vol. 1, Pg. 309, 1963.
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4 Total obstruction of the sinuses due to inflamed mucosa. (Patient 04)
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1 Axial computed tomography (CT) scans of the frontal sinus.
A: due to the long lasting pressure of mucus, the bone of the anterior wall of frontal sinus is thinned out and elevated anteriorly, forming a bulge. B: same situation as depicted in fig A: the posterior bony wall of frontal sinus is thinned out and extremely elevated posteriorly towards the frontal lobe of the brain. As depicted on the scan, a thin bony layer covering the dura could be recognized intraoperatively
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2 Same patient as 1 and 3, frontal CT
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D. 6 months later, tenacious yellow secretions in L basal bronchial division
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C. After suction the material was seen to extend distally – obstructing the right basal stem bronchus
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B. After suction the material was seen to extend distally – obstructing the right basal stem bronchus
