Secondary metabolites, 3D structure: Trivial name – fumitremorgin B

Date: 26 November 2013

Secondary metabolites, 3D structure: Trivial name – fumitremorgin B

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Notes:

Species: A. fumigatusSystematic name: 5H,14H-Pyrrolo[1”,2”:4′,5′]pyrazino[1′,2′:1,6]pyrido[3,4-b]indole-5,14-dione, 1,2,3,5a,6,11,12,14a-octahydro-5a,6-dihydroxy-9-methoxy-11-(3-methyl-2-butenyl)-12-(2-methyl-1-propenyl)-, (5aR,6S,12S,14aS)-Molecular formulae: C27H33N3O5Molecular weight: 479Chemical abstracts number: 12626-17-4Selected references: Yamazaki, Mikio; Suzuki, Kumiko; Fujimoto, Haruhiro; Akiyama, Toshiyuki; Sankawa, Ushio; Itaka, Yoichi (Res. Inst. Chemobiodyn., Chiba Univ., Chiba 280, Japan). Chem. Pharm. Bull., 28(3), 861-5 (English) 1980.


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  • A. versicolor by microscopy showing very long thin conidiophores.

    aspvers4

  • Pigmentation of Aspergillus versicolor colonies ranged from pale green to greenish-beige, pink-green, dark green and brown. Reverse is usually reddish. The growth rate is usually slow. Cultured on Sabouraud dextrose agar with chloramphenicol.

    aspvers3

  • A Colonies on MEA after one week; B, C conidial heads with tip of conidiophire, x920; D conidial head, x 2330; E conidial heads x920

    aspvers2

  • A Colonies on MEA + 20% sucrose after one week; B detail of colony showing columnar conidial heads x 44 ; C conidial heads x 920; D conidia x2330

    A

  • Scanning electron micrograph photo of conidia. Scale bar: 1 µm.

    piperis F

  • Conidia-forming head and culture plate

    A

  • Cultures are grown on malt extract agar for 5-7 days at 30°C.
    Light microscopy-1000x stained with lacto-phenol and cotton blue.

    niger

  • A Colonies on MEA +20% sucrose after one week; B ascomata x 40; C conidiophores x 920; D ascospores x2330; E ascoma x 230; F portion of ascoma with asci and ascospores, x 920.

    Aspergillus_chevalieri