Date: 26 November 2013
Secondary metabolites, 3D structure: Trivial name – fumagillin
Copyright: n/a
Notes:
Species: A. fumigatusMolecular formulae: C26H34O7Molecular weight: 458.55Chemical abstracts number: 23110-15-8Selected references: Antibiotics: Origin, Nature, and Properties, Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 3, Pg. 1834, 1978.Antibiotics and Chemotherapy Vol. 1, Pg. 54, 1951.Toxicity: Originally isolated because of its antibiotic properties, especially against protozoa such as Entamoeba histolytica. LD50 in mice 800 mg/kg body-weight subcutaneously although as much as 2 mg/kg body-weight could be tolerated orally.
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