Date: 26 November 2013
Secondary metabolites, 3D structure: Trivial name – Dechloronidulin
Copyright: n/a
Notes:
Species: A. fumigatus, Emericella unguisSystematic name: 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 3,8-dimethoxy-1,9-dimethyl-6-(1-methyl-1-propenyl)-, labeled with carbon-14 (9CI)Molecular formulae: C21H22O5Chemical abstracts number: 52721-93-4Selected references: Fungal depside, guisinol, from a marine derived strain of Emericella unguis Authors: Nielsen J.1; Nielsen P.H.; Frisvad J.C. Phytochemistry, Volume 50, Number 2, 26 January 1999, pp. 263-265(3)
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Drug rashes: Drug interactions between steroids and anti-fungal drugs – (ecchymosis)
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Reference: Muco-cutaneous retinoid effects and facial erythema related to the novel triazole antifungal agent voriconazole. Denning, DW & Griffiths, CEM. Clin.Exp Dermatol 2001, 26(8), 648-53.
Courtesy of Dr D Denning, Wythenshawe Hospital, Manchester.(© Fungal Research Trust),
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Micrographs of A. niger conidia & conidial heads provided by Amaliya Stepanova, Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.
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Micrographs of A. terreus conidia & conidial heads provided by Amaliya Stepanova, , Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.
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Micrographs of A. fumigatus conidia & conidial heads provided by Amaliya Stepanova, , Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.
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Patients has history of ABPA complicating long standing asthma. His total IgE has fluctuated between 2,200 and 4,600 KU/L, his Aspergillus IgE between 36.3 and 65.4 kAU/L and Aspergillus IgG from 87-154 mg/L. He has been taking long term itraconazole.
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