Date: 26 November 2013
Secondary metabolites, 3D structure: Trivial name – Candidusin C
Copyright: n/a
Notes:
Species: A. candidusSystematic name: 2,3-Dibenzofurandiol, 6,9-dimethoxy-7-(4-methoxyphenyl)-Molecular formulae: C21H18O6Molecular weight: 366Chemical abstracts number: 267007-58-9Selected references: Rahbaek, Lisa; Frisvad, Jens C.; Christophersen, Carsten (CORPORATE SOURCE Department of Chemistry, Marine Chemistry Section, University of Copenhagen, Copenhagen DK-2100, Den.). SOURCE Phytochemistry, 53(5), 581-586 (English) 2000 Elsevier Science Ltd.
Images library
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The chest x-ray shows a patient who had a left lung transplanted in May 2003 for cryptogenic fibrosing alveolitis, which was diagnosed post-transplant as sarcoidosis.
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Gross pathology demonstrating the great pleural thickness and two cavities (upper lobe and superior segment of lower lobe) with fragments of fungal mass.
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Histopathological appearance of a fungus ball. Note a conidial head resulting from fungal exposure to the air.
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Histopathological appearance of a fungus ball caused by Scedosporium apiospermum. The presence of anneloconidia differentiates it from Aspergillus.
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Chronic necrotising aspergillosis. Hyaline hyphal and calcium oxalate crystals obtained by needle aspirate biopsy from a diabetic patient with chronic necrotizing aspergillosis caused by Aspergillus niger (Papanicolaou, x 100).
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Aspergillus niger fungus ball and acute oxalosis. Higher magnification of adjacent replicate section.
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Oxalate crystals within renal tubuli (H&E, phase contrast, x 100). This patient developed acute oxalosis.
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Lung surface. Fungus ball, severe parenchymal fibrosis and pleural thickening.