Date: 26 November 2013
Secondary metabolites, 3D structure: Trivial name – Butyrolactone III 1,2-dichloroethane
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Species: A. terreusSystematic name: 2-Furancarboxylic acid, 2-[[(2R)-2,3-dihydro-2-(1-hydroxy-1-methylethyl)-5-benzofuranyl]methyl]-2,5-dihydro-4-hydroxy-3-(4-hydroxyphenyl)-5-oxo-, methyl ester, (2R)-, compd. with 1,2-dichloroethane (1:1)Molecular formulae: C24H24O8.C2H4Cl2Molecular weight: Chemical abstracts number: 271587-59-8Selected references: Rao, K. V.; Sadhukhan, A. K.; Veerender, M.; Ravikumar, V.; Mohan, E. V. S.; Dhanvantri, S. D.; Sitaramkumar, M.; Babu, J. Moses; Vyas, K.; Reddy, G. Om (CORPORATE SOURCE Dr. Reddy’s Research Foundation, Hyderabad 500 050, India). SOURCE Chem. Pharm. Bul
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Drug rashes: Drug interactions between steroids and anti-fungal drugs – (ecchymosis)
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Reference: Muco-cutaneous retinoid effects and facial erythema related to the novel triazole antifungal agent voriconazole. Denning, DW & Griffiths, CEM. Clin.Exp Dermatol 2001, 26(8), 648-53.
Courtesy of Dr D Denning, Wythenshawe Hospital, Manchester.(© Fungal Research Trust),
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Micrographs of A. niger conidia & conidial heads provided by Amaliya Stepanova, Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.
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Micrographs of A. terreus conidia & conidial heads provided by Amaliya Stepanova, , Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.
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Micrographs of A. fumigatus conidia & conidial heads provided by Amaliya Stepanova, , Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.
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Patients has history of ABPA complicating long standing asthma. His total IgE has fluctuated between 2,200 and 4,600 KU/L, his Aspergillus IgE between 36.3 and 65.4 kAU/L and Aspergillus IgG from 87-154 mg/L. He has been taking long term itraconazole.
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