Date: 26 November 2013
Secondary metabolites, 3D structure: Trivial name – Butyrolactone II
Copyright: n/a
Notes:
Species: A. terreusSystematic name: 2-Furancarboxylic acid, 2,5-dihydro-4-hydroxy-3-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-5-oxo-, methyl ester, (2R)-Molecular formulae: C19H16O7Molecular weight: 356Chemical abstracts number: 87414-44-6Selected references: Metabolic products of Aspergillus terreus. IX. Biosynthesis of butyrolactone derivatives isolated from strains IFO 8835 and 4100. Nitta, Keiichi; Fujita, Noritaka; Yoshimura, Tadashi; Arai, Kunizo; Yamamoto, Yuzuru. Fac. Pharm. Sci., Kanazawa Univ., Kanazawa, Japan. Chemical & Pharmaceutical Bulletin (1983), 31(5), 1528-33.
Images library
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BAL specimen showing hyaline, septate hyphae consistent with Aspergillus, stained with Blankophor
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Mucous plug examined by light microscopy with KOH, showing a network of hyaline branching hyphae typical of Aspergillus, from a patient with ABPA.
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Corneal scraping stained with lactophenol cotton blue showing beaded septate hyphae not typical of either Fusarium spp or Aspergillus spp, being more consistent with a dematiceous (ie brown coloured) fungus
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Corneal scrape with lactophenol cotton blue shows separate hyphae with Fusarium spp or Aspergillus spp.
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A filamentous fungus in the CSF of a patient with meningitis that grew Candida albicans in culture subsequently.
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Transmission electron micrograph of a C. neoformans cell seen in CSF in an AIDS patients with remarkably little capsule present. These cells may be mistaken for lymphocytes.
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India ink preparation of CSF showing multiple yeasts with large capsules, and narrow buds to smaller daughter cells, typical of C. neoformans