Date: 26 November 2013
Secondary metabolites, 3D structure: Trivial name – Butanedioic acid
Copyright: n/a
Notes:
Species: A. nigerSystematic name: Butanedioic acid, hexylmethylene-, (2R)-Molecular formulae: C11H18O4Molecular weight: 214Chemical abstracts number: 94513-51-6Selected references: Varoglu, Mustafa; Crews, Phillip. Biosynthetically diverse compounds from a saltwater culture of sponge-derived Aspergillus niger. Journal of Natural Products (2000), 63(1), 41-43. CODEN: JNPRDF ISSN:0163-3864. CAN 132:163229 AN 1999:807554
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Drug rashes: Drug interactions between steroids and anti-fungal drugs – (ecchymosis)
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Reference: Muco-cutaneous retinoid effects and facial erythema related to the novel triazole antifungal agent voriconazole. Denning, DW & Griffiths, CEM. Clin.Exp Dermatol 2001, 26(8), 648-53.
Courtesy of Dr D Denning, Wythenshawe Hospital, Manchester.(© Fungal Research Trust),
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Micrographs of A. niger conidia & conidial heads provided by Amaliya Stepanova, Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.
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Micrographs of A. terreus conidia & conidial heads provided by Amaliya Stepanova, , Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.
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Micrographs of A. fumigatus conidia & conidial heads provided by Amaliya Stepanova, , Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.
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Patients has history of ABPA complicating long standing asthma. His total IgE has fluctuated between 2,200 and 4,600 KU/L, his Aspergillus IgE between 36.3 and 65.4 kAU/L and Aspergillus IgG from 87-154 mg/L. He has been taking long term itraconazole.
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