Secondary metabolites, 3D structure: Trivial name – Astepyrone metabolite 2

Corneal ulcer – gram stain. Corneal scrapings were taken from a 67 yr old farmer presenting with a corneal ulcer of the right eye. A piece of vegetable matter was embedded in the cornea and scrapings were done. Gram stain (500x magnification) showed

Corneal ulcer – gram stain. Corneal scrapings were taken from a 67 yr old farmer presenting with a corneal ulcer of the right eye. A piece of vegetable matter was embedded in the cornea and scrapings were done. Gram stain (500x magnification) showed numerous septate hyphae. Cultures grew a small amount of A fumigatus.

Corneal ulcer – gram stain. Corneal scrapings were taken from a 67 yr old farmer presenting with a corneal ulcer of the right eye. A piece of vegetable matter was embedded in the cornea and scrapings were done. Gram stain (500x magnification) showed

Corneal ulcer – gram stain. Corneal scrapings were taken from a 67 yr old farmer presenting with a corneal ulcer of the right eye. A piece of vegetable matter was embedded in the cornea and scrapings were done. Gram stain (500x magnification) showed numerous septate hyphae. Cultures grew a small amount of A fumigatus.

Corneal ulcer – gram stain. Corneal scrapings were taken from a 67 yr old farmer presenting with a corneal ulcer of the right eye. A piece of vegetable matter was embedded in the cornea and scrapings were done. Gram stain (500x magnification) showed

Corneal ulcer – gram stain. Corneal scrapings were taken from a 67 yr old farmer presenting with a corneal ulcer of the right eye. A piece of vegetable matter was embedded in the cornea and scrapings were done. Gram stain (500x magnification) showed numerous septate hyphae. Cultures grew a small amount of A fumigatus.

Aspergillus keratitis. Central lesion in aspergillus keratitis following a corneal foreign body which made a good response to topical treatment alone, albeit over 2 months intensive treatment.

Aspergillus keratitis. Central lesion in aspergillus keratitis following a corneal foreign body which made a good response to topical treatment alone, albeit over 2 months intensive treatment.

Aspergillus keratitis. B- Severe central aspergillus infection with a “cheesey” looking area of the lesion and hypopyon (fluid level of inflammatory cells in the anterior chamber)

Aspergillus keratitis. B- Severe central aspergillus infection with a “cheesey” looking area of the lesion and hypopyon (fluid level of inflammatory cells in the anterior chamber)

Aspergillus keratitis. A- Severe aspergillus infection with large area of corneal ulceration and deep stromal involvement

Aspergillus keratitis. A- Severe aspergillus infection with large area of corneal ulceration and deep stromal involvement

Candida keratitis. Focal candida keratitis as an unusual cause of a suture related infection following corneal transplantation for non infective indication

Candida keratitis. Focal candida keratitis as an unusual cause of a suture related infection following corneal transplantation for non infective indication

Candida keratitis. Subacute onset of candida keratitis in a young adult in whom dust blew into her eye in Greece. A slightly “feathery” edge to stromal involvement is suggestive of fungal infection

Candida keratitis. Subacute onset of candida keratitis in a young adult in whom dust blew into her eye in Greece. A slightly “feathery” edge to stromal involvement is suggestive of fungal infection

Aspergillus endopthalmitis. Temporal necrosis due to Aspergillus endopthalmitis as part of disseminated disease. No evidence of vitritis. Systemic treatment essential.

Aspergillus endopthalmitis. Temporal necrosis due to Aspergillus endopthalmitis as part of disseminated disease. No evidence of vitritis. Systemic treatment essential.

Aspergillus endopthalmitis. Large scarred area of the choroid following healing after Aspergillus endopthalmitis

Aspergillus endopthalmitis. Large scarred area of the choroid following healing after Aspergillus endopthalmitis