Secondary metabolites, 3D structure: Trivial name – aflatoxin P1

Date: 26 November 2013

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Secondary metabolites, 3D structure: Trivial name – aflatoxin P1

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Notes:

Species: A. flavusSystematic name: Cyclopenta[c]furo[3′,2′:4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-hydroxy-, (6aR-cis)Molecular formulae: C16H10O6Molecular weight: 298Chemical abstracts number: 32215-02-4Selected references: Nakazato, Mitsuo; Morozumi, Satoshi; Saito, Kazuo; Fujinuma, Kenji; Nishima, Taichiro; Kasai, Nobuhiko (Dep. Food Hyg. and Nutr., Tokyo Metrop. Res. Lab. Public Health, Tokyo 169, Japan). Eisei Kagaku, 37(2), 107-16 (English) 1991.

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Showing 10 posts of 2574 posts found.

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  • Papular rash with CPA

    Drug rashes: Drug interactions between steroids and anti-fungal drugs – (ecchymosis)

    Image A: Red skin rash on arms due to effect of inhaled steroids termed ecchymosis., Image B: Red skin rash on arms due to effect of inhaled steroids termed ecchymosis., Image C: Papular rash with blisters on the back, associated with CPA but prior to treatment, rash appeared 2 years previously in October 2007. The rash resolved on treatment with azoles., Image D: Papular rash with blisters on the back, associated with CPA but prior to treatment, rash appeared 2 years previously in October 2007. The rash resolved on treatment with azoles.

  • Facial erythema: Side effects of anti-fungal drugs – drug rashes

    Reference: Muco-cutaneous retinoid effects and facial erythema related to the novel triazole antifungal agent voriconazole. Denning, DW & Griffiths, CEM. Clin.Exp Dermatol 2001, 26(8), 648-53.
    Courtesy of Dr D Denning, Wythenshawe Hospital, Manchester.(© Fungal Research Trust)

    Patient AB: Voriconazole rash. Following 8 weeks of Voriconazole, patient had remarkable facial erythema, most consistent with sun exposure because of sparing of her neck., Patient AB: Voriconazole rash. Following 8 weeks of Voriconazole, patient had remarkable facial erythema, most consistent with sun exposure because of sparing of her neck., Patient AB: Discoid lupus erythematosus following 12 months voriconazole therapy. This improved with use of sunblock factor 30 and resolved after discontinuation of voriconazole, 2 months later.

  • Cresemba

    Cresemba (Isavuconazole)

  • Germinating spores of Aspergillus fumigatus

    Germinating spores of Aspergillus fumigatus

  • Aspergillus niger

    Micrographs of A. niger conidia & conidial heads provided by Amaliya Stepanova, Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.

    A niger conidial head TEM in vitro (РКПГF-1124), A niger mature conidium TEM in vitro (РКПГF-1124)

  • Aspergillus terreus

    Micrographs of A. terreus conidia & conidial heads provided by Amaliya Stepanova, , Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.

    A terreus aleurospore TEM in vitro (РКПГF-1275), A terreus mature conidium SEM in vitro (РКПГ-1275), A terreus mature conidial head SEM in vitro

  • Electron Microscopy: Aspergillus fumigatus

    Micrographs of A. fumigatus conidia & conidial heads provided by Amaliya Stepanova, , Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.

    Conidial head (SEM), Part of conidial head (SEM), Mature conidia (SEM), Hyphae (SEM), Murine lung tissue (TEM)

  • Aspergillus clavatus

    Isolate from environmental sample

    A. clavatus, A. clavatus, A. clavatus

  • ABPA complicated by severe varicose bronchiectasis

    Patients has history of ABPA complicating long standing asthma. His total IgE has fluctuated between 2,200 and 4,600 KU/L, his Aspergillus IgE between 36.3 and 65.4 kAU/L and Aspergillus IgG from 87-154 mg/L. He has been taking long term itraconazole.

    December 2012, May 2012, AW CT Dec 2012 2, February 2010

  • Ira F. Salkin 1941-2016

    Ira F. Salkin 1941-2016