Secondary metabolites, 3D structure: Trivial name – aflatoxin P1

Date: 26 November 2013

Secondary metabolites, 3D structure: Trivial name – aflatoxin P1

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Notes:

Species: A. flavusSystematic name: Cyclopenta[c]furo[3′,2′:4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-hydroxy-, (6aR-cis)Molecular formulae: C16H10O6Molecular weight: 298Chemical abstracts number: 32215-02-4Selected references: Nakazato, Mitsuo; Morozumi, Satoshi; Saito, Kazuo; Fujinuma, Kenji; Nishima, Taichiro; Kasai, Nobuhiko (Dep. Food Hyg. and Nutr., Tokyo Metrop. Res. Lab. Public Health, Tokyo 169, Japan). Eisei Kagaku, 37(2), 107-16 (English) 1991.

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Immune reconstitution syndrome (mucous impaction or obstructing bronchial aspergillosis) complicating pulmonary aspergillosis in AIDS.

Chest X ray (+64 days)
Immune reconstitution syndrome (mucous impaction or obstructing bronchial aspergillosis) complicating pulmonary aspergillosis in AIDS.

Chest X ray (+day 42)
Immune reconstitution syndrome (mucous impaction or obstructing bronchial aspergillosis) complicating pulmonary aspergillosis in AIDS

Chest X ray (+day 14)
Orbital aspergillosis with late fungemia
Chronic fibrosing pulmonary aspergillosis

Chronic fibrosing pulmonary aspergillosis pt RS.
Pleural thickening followed by CNPA

Image G. 14/5/99
Showing progression of the cavity with some debris inside
Pleural thickening followed by CNPA

Image F. 14/5/99
Compare with B, showing progressive enlargement of cavity and formation of fungal ball.
Pleural thickening followed by CNPA

Image E 14/5/99
Showing enlargement of cavity at left apex and formation of a new cavity there.
Pleural thickening followed by CNPA

Image D 30/3/99
One medium sized irregular cavity at left apex
Pleural thickening followed by CNPA

Image C. 30/3/99
Parenchymal or pleural disease adjacent to the mediasternum on the left with diffuse parenchymal disease. Also pleural based nodules bilaterally.