RAPD profiles of 14 A fumigatus isolates from Swedish and New Zealand saw mills, generated with primer R108. Mwt markers (lambda with Pst1) indicated by M.
RAPD profiles of 14 A fumigatus isolates from Swedish and New Zealand saw mills, generated with primer R108. Mwt markers (lambda with Pst1) indicated by M.
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Notes:
Kindly reproduced from Birch et al, J Hosp Infect 1995; 30(Suppl):339-351
Mr RM is 80 and an ex-coal miner.He developed pneumoconiosis from exposure to coal dust. He also developed rheumatoid arthritis and the combination of this disease and pneumoconiosis is called Caplan’s syndrome.
His chest Xray in early 2015 shows extensive bilateral pulmonary shadowing with solid looking nodules superimposed on abnormal lung fields, contraction of his left lung with an elevated diaphragm and a large left upper lobe aspergilloma, displaying a classic air crescent. His CT scan from mid 2014 demonstrates a large aspergilloma in a cavity on the left, with marked pleural thickening around it, which is partially ‘calcified’ towards its base. Inferiorly on other images,remarkable pleural thickening and fibrotic irregular and spiculated nodules are seen, most partially calcified.