pt MN Cerebral aspergillosis, child ALL

Date: 26 November 2013

  • Image A. Contrast enhanced scan of the brain in a 5 year old child who had a convulsion several weeks after starting chemotherapy for acute lymphoblastic leukaemia.

  • Image B. CT scan of the brain more than 12 months after the diagnosis of cerebral aspergillosis was made, showing remarkable resolution of disease with daily amphotericin B and flucytosine, and continued chemotherapy for his leukaemia.

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Further details

Image A. Multiple ring enhancing abscesses with substantial surrounding oedema was demonstrated. He had no focal neurological deficits. A needle aspiration confirmed the clinical impression of cerebral aspergillosis by culture and microscopy.

Image B. Resolution of cerebral aspergillosis, pt MN.  Focal scars with some surrounding oedema are seen in the site of the prior abscesses. 

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