Date: 26 November 2013
Transverse sections through the thorax of a patient with AIDS, hepatitis C and a left tempero-parietal cerebral lymphoma. His CD4 cell count was 45 x 106 / l. The lymphoma was proven by biopsy after a poor response to anti-toxoplasma therapy. He was given dexamethasone to cover the surgery and then developed diabetes mellitus. He did not receive chemotherapy for his lymphoma but did have 2 cerebral radiotherapy treatments (1.8 Gy each). Three weeks after the biopsy he developed dyspnoea and fever. Shortly after this he developed a right-sided hemiparesis, became comatose and died 2 days later.Autopsy showed a cerebral lymphoma and pulmonary and renal aspergillosis. Aspergillus nidulans was recovered from cultures of lungs and kidney.
Copyright:
Images submitted by Dr. Cornelia Lass-Floerl, University of Innsbruck – Institute of Hygiene; the case team includes: Dr. Mario Sarcletti, Dr. Alfons Stöger and Prof. Hans Maier all at the University of Innsbruck.
Notes: n/a
Images library
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Title
Legend
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Emericella nidulans (Eidam), Anamorph: Aspergillus nidulans (Eidam) – Hulle cells
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Emericella nidulans (Eidam), Anamorph: Aspergillus nidulans (Eidam)
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Emericella nidulans (Eidam), Anamorph: Aspergillus nidulans (Eidam)
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Emericella nidulans (Eidam), Anamorph: Aspergillus nidulans (Eidam)
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Spitzenkorper; phase contrast micrograph of A.nidulans after one day grown at 25°C in minimal media containing 17% gelatin showing spitzenkorper and fungal cell morphology
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Interference contrast micrograph of A.nidulans after one day at 25°C in minimal media containing 17% gelatin
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Hyphal growth. Micro-colony of A.nidulans grown overnight at 25°C in minimal media containing 17% gelatin
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Mitochondria organisation: GFP fluorescence micrographs showing mitochondrial organisation in an A.nidulans strain with GFP mitochondria, grown at 25°C in minimal media.
