Date: 26 November 2013
Transverse sections through the thorax of a patient with AIDS, hepatitis C and a left tempero-parietal cerebral lymphoma. His CD4 cell count was 45 x 106 / l. The lymphoma was proven by biopsy after a poor response to anti-toxoplasma therapy. He was given dexamethasone to cover the surgery and then developed diabetes mellitus. He did not receive chemotherapy for his lymphoma but did have 2 cerebral radiotherapy treatments (1.8 Gy each). Three weeks after the biopsy he developed dyspnoea and fever. Shortly after this he developed a right-sided hemiparesis, became comatose and died 2 days later.Autopsy showed a cerebral lymphoma and pulmonary and renal aspergillosis. Aspergillus nidulans was recovered from cultures of lungs and kidney.
Copyright:
Images submitted by Dr. Cornelia Lass-Floerl, University of Innsbruck – Institute of Hygiene; the case team includes: Dr. Mario Sarcletti, Dr. Alfons Stöger and Prof. Hans Maier all at the University of Innsbruck.
Notes: n/a
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Image g. 3 yr old boy with CNS aspergillosis pt TS. Scan 6 weeks post treatment.
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Image f. 3 yr old boy with CNS aspergillosis pt TS. Scan 6 weeks post treatment
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Image e. 3 yr old boy with CNS aspergillosis pt TS. Scan 6 weeks post treatment.
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Image d. 3 yr old boy with CNS aspergillosis pt TS. MRI scan pre-amphotericin B
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Image c. 3 yr old boy with CNS aspergillosis pt TS. MRI scan pre-amphotericin B
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Image b. 3 yr old boy with CNS aspergillosis pt TS. MRI scan pre-amphotericin B.
