Date: 26 November 2013
Transverse sections through the thorax of a patient with AIDS, hepatitis C and a left tempero-parietal cerebral lymphoma. His CD4 cell count was 45 x 106 / l. The lymphoma was proven by biopsy after a poor response to anti-toxoplasma therapy. He was given dexamethasone to cover the surgery and then developed diabetes mellitus. He did not receive chemotherapy for his lymphoma but did have 2 cerebral radiotherapy treatments (1.8 Gy each). Three weeks after the biopsy he developed dyspnoea and fever. Shortly after this he developed a right-sided hemiparesis, became comatose and died 2 days later.Autopsy showed a cerebral lymphoma and pulmonary and renal aspergillosis. Aspergillus nidulans was recovered from cultures of lungs and kidney.
Copyright:
Images submitted by Dr. Cornelia Lass-Floerl, University of Innsbruck – Institute of Hygiene; the case team includes: Dr. Mario Sarcletti, Dr. Alfons Stöger and Prof. Hans Maier all at the University of Innsbruck.
Notes: n/a
Images library
-
Title
Legend
-
Nasal, sinus and orbital aspergillosis in a cat. Nose- severe bone erosion rostrally through the nasal bone.
-
Aspergillosis in penguins. Lesions found in captive Magellanic penguins (Spheniscus magellanicus) with aspergillosis as determined by histology.Hyaline, septate and branching hyphae, and asexual reproductive structure of Aspergillus observed in the tissues of Magellanic penguin with fatal aspergillosis. (PAS stain )
-
Aspergillosis in penguins. Lesions found in captive Magellanic penguins (Spheniscus magellanicus) with aspergillosis as determined by histology. Hyaline, septate and branching hyphae, and asexual reproductive structure of Aspergillus observed in the tissues of Magellanic penguin with fatal aspergillosis. (Grocott’s stain)
-
Aspergillosis in penguins. Multiple granulomatous nodules at syrinx with necrotic debris and caseous exudates. These lesions were responsible for partial obstruction of the air passages.
-
Aspergillosis in penguins. Lesions found in captive Magellanic penguins (Spheniscus magellanicus) with aspergillosis as determined by histology. Larges masses formed by multiple nodules in the air sacs and in the adrenal gland.
-
Aspergillosis in penguins. Lesions found in captive Magellanic penguins (Spheniscus magellanicus) with aspergillosis as determined by histology.Adrenal gland involvement (adjacent to kidney) – characterized by massive enlargement to 8-10 cm, formed by multiple granulomatous nodules.
-
Aspergillosis in penguins Lesions found in captive Magellanic penguins (Spheniscus magellanicus) with aspergillosis as determined by histology.Adrenal gland involvement (adjacent to kidney) – characterized by massive enlargement to 8-10 cm, formed by multiple granulomatous nodules.
-
Aspergillosis in penguins. Lesions found in captive Magellanic penguins (Spheniscus magellanicus) with aspergillosis as determined by histology.Adrenal gland involvement (adjacent to kidney) – characterized by massive enlargement to 8-10 cm, formed by multiple granulomatous nodules.
-
Aspergillosis in penguins. Multiple granulomatous nodules in the surface of the kidney
-
Aspergillosis in penguins. Lesions found in fatal cases of captive Magellanic penguins (Spheniscus magellanicus) with aspergillosis. Multiple granulomatous nodules in the parenchyma, characterized by friable necrotic lesions with distorted anatomy of the organ.