Date: 26 November 2013
Halo sign in IPA
Copyright: n/a
Notes:
CT scan of a neutropenia patient with leukaemia who has 2 lesions. One, on the right, is nodular, abuts on the pleura and is surrounded by a (grey) low attenuation area, referred to as the “halo” sign. This is virtually only seen in invasive fungal infections of the lung, especially early in the course of the disease, during neutropenia. The other lesion visible on this scan, posteriorly on the left, is also typical of invasive pulmonary aspergillosis in that it is pleura-based and has sharply angulated sides typical of vascular invasion and infarction of small lung segments. There is the suggestion of a “halo” sign anteriorly, but there is less confidence in this appearance (compared with the other) because it is only on one side of the lesion.
Images library
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Clothing spreads Aspergillus spores – Scanning electron micrograph of Aspergillus niger spores on cotton fibres.
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Clothing spreads Aspergillus spores – Scanning electron micrograph of Aspergillus niger spores on wool fibres.
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A Colonies on MEA after one week;B conidial heads and tip of conidiophore, x 230; C conidial head, x920; E conidial head, x920. Copyright B.Flannigan, R Samson & JD Miller (From Microorganisms in home and indoor work environments, Published by Taylor and Francis)
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3 yr old boy with CNS aspergillosis pt TS. Scan 6 weeks post treatment.
