Date: 26 November 2013
Halo sign in IPA
Copyright: n/a
Notes:
CT scan of a neutropenia patient with leukaemia who has 2 lesions. One, on the right, is nodular, abuts on the pleura and is surrounded by a (grey) low attenuation area, referred to as the “halo” sign. This is virtually only seen in invasive fungal infections of the lung, especially early in the course of the disease, during neutropenia. The other lesion visible on this scan, posteriorly on the left, is also typical of invasive pulmonary aspergillosis in that it is pleura-based and has sharply angulated sides typical of vascular invasion and infarction of small lung segments. There is the suggestion of a “halo” sign anteriorly, but there is less confidence in this appearance (compared with the other) because it is only on one side of the lesion.
Images library
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A.fumigatus conidium. Scanning electron micrograph of an A.fumigatus conidium showing the fascicles of hydrophobic rodlets covering the surface
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Scanning electron microscope image of A. lentulus conidiophore Magnification 2000X
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Aspergillus lentulus. Differential interphase contrast microscopy microscopy images of conidial heads of A.lentulus . Magnification 60X.
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Allergic Aspergillus Sinusitis -Patient AM. C – Extensive involvement of both maxillary sinuses, with soft tissue swelling. Swelling of both turbinates also visible.
