Date: 7 February 2014
Image B
Copyright:
Dr D Denning, Wythenshawe Hospital, Manchester.(© Fungal Infection Trust)
Notes:
Patient BC
A petite women in her 50’s with severe asthma and fungal sensitization (SAFS) had been unable to tolerate either itraconazole or voriconazole for any length of time, and was severely disabled with her symptoms. One treatment option which is occasionally helpful is to give nebulised amphotericin B (link to video of Helen). She was given 10mg of amphotericin B deoxycholate in water through a Pari LC nebulizer, supervised by a senior physiotherapist. Shortly after starting this, she felt much more breathless and the nebulizer was stopped. Salbutamol rescue was administered. After about 40 minutes she recovered.
The spirometer readings show a starting FEV1 of 2.35 L/sec. This fell to 1.05 L/sec, a dramatic fall with amphotericin B nebulisation. (Image A) She recovered with salbutamol to 2.25 L/sec. (Image B)
Images library
Showing 10 posts of 2574 posts found.
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Scanning electron microscope image of A. lentulus conidiophore Magnification 2000X
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Aspergillus lentulus. Differential interphase contrast microscopy microscopy images of conidial heads of A.lentulus . Magnification 60X.
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Allergic Aspergillus Sinusitis -Patient AM. C – Extensive involvement of both maxillary sinuses, with soft tissue swelling. Swelling of both turbinates also visible.
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Allergic Aspergillus Sinusitis -Patient AM. D – Marked involvement of ehmoidal air cells on the right , together with the inferior aspect of the sphenoid sinus. The left side is almost clear of disease.
