Date: 7 February 2014
Image B
Copyright:
Dr D Denning, Wythenshawe Hospital, Manchester.(© Fungal Infection Trust)
Notes:
Patient BC
A petite women in her 50’s with severe asthma and fungal sensitization (SAFS) had been unable to tolerate either itraconazole or voriconazole for any length of time, and was severely disabled with her symptoms. One treatment option which is occasionally helpful is to give nebulised amphotericin B (link to video of Helen). She was given 10mg of amphotericin B deoxycholate in water through a Pari LC nebulizer, supervised by a senior physiotherapist. Shortly after starting this, she felt much more breathless and the nebulizer was stopped. Salbutamol rescue was administered. After about 40 minutes she recovered.
The spirometer readings show a starting FEV1 of 2.35 L/sec. This fell to 1.05 L/sec, a dramatic fall with amphotericin B nebulisation. (Image A) She recovered with salbutamol to 2.25 L/sec. (Image B)
Images library
Showing 10 posts of 2574 posts found.
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This is an ultrasound image showing retina and subretinal mass due to Aspergillus
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Corneal ulcer due to Aspergillus fumigatus occurring after injury from rose thorn in the garden
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The external eye shows gross conjunctival chemosis from a panophthalmitis due to Aspergillus
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Aspergillus onychomycosis caused by Aspergillus fumigatus.
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This photo shows extensive infection of the burn wound on the leg of a 7 year old boy, acquired about 3 weeks after the injury. Despite medical therapy he died.
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