This patient with chronic pulmonary aspergillosis failed itraconazole and was treated with oral voriconazole. She developed facial erythema with remarkable redness of her eyes. She had a sensation of mild irritation of the eyes. Voriconazole treatment was continued.
Mucous containing Charcot-Leyden crystals, stained with H & EA 57 year old woman presented with breathlessness. She had a history of mild asthma for which she occasionally took salbutamol inhaler puffs. The patient underwent a pneumonectomy because of the severity of her disease process, and uncertainty about the diagnosis, prior to serology results being obtained.Serology showed an IgE of 2600, with a strongly positive Aspergillus RAST test and weakly positive Aspergillus precipitins. Material re