Date: 26 November 2013
Four colonies of Aspergillus on an agar plate containing rose bengal (to limit colony spending) and elastin fibres (light pink dots). Underneath and surrounding the colonies, the elastin fibres have gone, indicating enzymatic degradation
Copyright:
© Denning DW, Elliott J, Keaney M. Temperature-dependent expression of elastase in Aspergillus species. J Med Vet Mycol, 1993;31:455-458.
Notes:
The medium was described by: Kothary MH, Chase T, Macmillan JD. Correlation of elastase production by some strains of Aspergillus fumigatus with ability to cause pulmonary invasive aspergillosis in mice. Infect Immun 1984; 43:320-3235.
Images library
-
Title
Legend
-
Aspergillus flavus Link. A colonies after 1 weekB,C conidial heads x 920D Conidia x920 E Conidial head x920
-
Patient diagnosed with Stage C Chronic Lymphocytic Leukaemia, treated in the MRC CLL4 study, with prednisolone for 4 weeks followed by oral chlorambucil for 7 days. Patient developed severe pneumonia due to pseudomonas and staphylococcus. Following treatment with broad spectrum antibiotics and 1 week of Abelcet, patient was readmitted with headache, disorientation and fever. CT brain scans showed 3 ring enhancing lesions, aspirated material showed neutrophils but grew aspergillus. Patient now improved on Abelcet (4 mg/kg) and oral itrconazole suspension 200mg b.d.
Thanks to Richard Chasty, Consultant Haematologist, North Staffordsire Hospital, UK.
, 
![Asp[1]niger](https://www.aspergillus.org.uk/wp-content/uploads/2013/11/Asp1niger-150x150.gif "Asp[1]niger")
